Impact of expiratory strength training in amyotrophic lateral sclerosis

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Impact of expiratory strength training in amyotrophic lateral sclerosis.

INTRODUCTION We evaluated the feasibility and impact of expiratory muscle strength training (EMST) on respiratory and bulbar function in persons with amyotrophic lateral sclerosis (ALS). METHODS Twenty-five ALS patients participated in this delayed intervention open-label clinical trial. Following a lead-in period, patients completed a 5-week EMST protocol. Outcome measures included: maximum ...

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Increasing peak expiratory flow time in amyotrophic lateral sclerosis.

BACKGROUND Serial measurements of pulmonary function to indicate decreasing respiratory muscle strength in patients with amyotrophic lateral sclerosis (ALS) is well documented. Quantitative outcome measures include declining FVC, FEV1, maximal inspired pressure, maximal expired pressure, and maximal voluntary ventilation. Increasing peak expiratory flow time (PEFT) may represent a further sensi...

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We examined the impact of expiratory muscle strength training on maximum expiratory pressure, cough spirometry, and disease progression in a 71-year-old male with amyotrophic lateral sclerosis. Maximum expiratory pressure declined 9% over an 8-week sham training period, but subsequently improved by 102% following 8 weeks of expiratory muscle strength training. Improvements in cough spirometry a...

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ژورنال

عنوان ژورنال: Muscle & Nerve

سال: 2016

ISSN: 0148-639X

DOI: 10.1002/mus.24990